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Thalassemia & Hemoglobinopathy Program

Payson 6 unit

The Pediatric Thalassemia & Hemoglobinopathy Program follows children with inherited conditions such as thalassemia, sickle cell anemia, spherocytosis, and other red cell disorders, including children with anemia and iron excess/deficiency.  We are able to provide transfusions on an outpatient basis, and have state-of-the-art radiology facilities for procedures like MRI for assessing tissue iron. Ongoing clinical trials in thalassemia are investigating the safety and efficacy of novel treatments which have the potential for significantly reducing the burden of this condition.

Services & Programs

Comprehensive Thalassemia Center

Our Comprehensive Thalassemia Center is the oldest and one of the largest centers of its kind in the United States.  Individuals with thalassemia receive their transfusions in a new state-of-the-art day hospital setting, with a multidisciplinary team providing psychosocial services, thalassemia screening, and genetic counseling.  

Directed by Dr. Sujit Sheth, the New York Comprehensive Thalassemia Center coordinates and links multiple services with the assistance of a nurse coordinator and a collaborative team of pediatric consultants including cardiologists, endocrinologists and gastroenterologists. Services are also provided by genetic counselors, social workers and psychologists. Optimal care requires routine surveillance and monitoring of patients’ conditions, treatment response, efficacy, safety and early interventions to minimize complications. A complex network of linked services are provided, ranging from screening, diagnosis, genetic counseling, prenatal diagnosis and psychosocial services, to specialized medical care and stem cell transplantation. 

Transition Program

Many age-related health issues arise as patients with thalassemia transition from childhood into adulthood, including delayed puberty, fertility complications and early-onset osteoporosis. Transitioning is crucial to maintaining continuity of care and providing patients with best possible outcomes as adults.

Our team works with transitioning patients to increase their knowledge about their disease, discuss the importance of keeping appointments and calling the thalassemia center about any problems, encourage compliance and self-administration of medications and/or treatments with less parental involvement, and eventually transfer decision-making from parents to patients.  This process gradually encourages more independent patient treatments and self-sufficient care.

Adult Transfusion Program

The adult transfusion program is located on the 3rd floor of the Starr Pavilion at the NewYork-Presbyterian Hospital/Weill Cornell Medical Center (NYPH/WCMC). To accommodate the needs of our adult population, this state-of-the-art facility conducts several transfusion sessions per week, including two evening sessions that allow patients to attend college classes or go to work during the day. As our patients with thalassemia survive longer through improvements in blood supply, transfusion therapy and iron chelation, they may require specialists to monitor for potential complications. These include cardiologists, endocrinologists, infectious disease specialists, hepatologists, nephrologists and others. Emergency services are available 24 hours per day, and a telephone answering service is available after the clinic is closed. 

Iron Chelation

A home care program for the administration of iron chelation is also coordinated within the Comprehensive Thalassemia Center. 24-hour emergency services, a telephone answering service, and access to hospital care for emergencies are available through the ER service at NYPH.


Diagnosis & Treatment

Our treatment center coordinates and links multiple services with the assistance of a nurse coordinator and a collaborative team of pediatric consultants including cardiologists, endocrinologists and gastroenterologists.  Services are also provided by genetic counselors, social workers and psychologists.

We administer red blood cell transfusions and timely initiation of iron chelation to prevent the complications of transfusional iron overload. Quarterly, comprehensive evaluations and annual studies are provided to address the regular surveillance, monitoring, prevention and treatment of hepatic, endocrine and cardiac complications related to iron overload and the potential infectious contamination or alloimmunization from transfusions.

Sujit Sheth

Sujit Sheth, M.D.

Vice Chair of Clinical Research, Department of Pediatrics
Chief, Pediatric Hematology/Oncology
Harold Weill Professor of Pediatric Hematology
Professor of Clinical Pediatrics
Attending Pediatrician
Shipra Kaicker

Shipra Kaicker, M.D.

Assistant Professor of Clinical Pediatrics
Assistant Attending Pediatrician
Headshot of Dorothy Kleinert

Dorothy Kleinert, N.P.

Nurse Practitioner

What Sets us Apart

  • As one of the longest-standing care centers in the country, we have extensive experience and expertise in treating thalassemia.
  • New York State Department of Health has recognized our practice as a designated Hemoglobinopathy Specialty Center providing comprehensive care to children and adolescents with disorders such as the thalassemia syndromes, sickle cell anemia, and other red blood cell disorders.
  • The New York Comprehensive Thalassemia Center has a rich history of participating in and conducting clinical trials resulting in major advances in care and improvement in outcomes through a reduction in disease.
Thalassemia, Hemoglobinopathy and Red Blood Cell Disorders Program
Division of Pediatric Hematology/Oncology
525 East 68th Street, Payson 695
New York, NY 10065
(212) 746-3400
(212) 746-3892

Pediatrics Weill Cornell Medicine Appointments & Referrals: (646) 962-KIDS (646) 962-5437 Chair's Office: Weill Cornell Medicine 525 E 68th St.
Box 225
New York, NY 10065 (646) 962-5437