Congratulations to Deyin D. Hsing, MD on receiving the Department of Pediatrics 2022 Young Investigators Award for her translational research project, Annexin A2 As a Potential Mediator in Development of Multi-organ Dysfunction in Children Following Cardiopulmonary Bypass.
Annexin A2 is an intracellular protein that’s instrumental in the maintenance of vascular homeostasis. For this project, Dr. Hsing will study how the degradation of annexin A2 during cardiopulmonary bypass contributes to the development of early organ dysfunction in children, with a special focus on how it impacts respiratory function in the early postoperative period. The study will help researchers better understand the pathobiology underlying bypass-induced organ dysfunction through the identification of new molecular targets, with the goal of informing future interventions in combating the harmful effects of systemic inflammation associated with cardiopulmonary bypass.