Weill Cornell Medicine was awarded a $4.2 million Program Project Grant renewal from the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID). This will fund the development of a vaccine that can prevent the cytomegalovirus (CMV) from being transmitted from mother to baby during pregnancy—the most common congenital infection worldwide.
The prestigious Program Project Grant has the possibility to be extended for a total of five years and $20.4 million to support collaborative, multi-project research toward effective information sharing and research synergy that may speed the path to a vaccine.
Several companies, like Moderna and Merck, are testing vaccines for their ability to protect pregnant women from CMV infection, thereby reducing the chances of transmission to the fetus. However, Dr. Sallie Permar, the chair of the Department of Pediatrics at Weill Cornell Medicine, is leading the program to test vaccine approaches that will prevent transmission of the virus to protect the developing fetus.
Worldwide, about one in 200 babies is born with CMV and one-quarter of them experience long-lasting impairments, including hearing loss, smaller than average head size (microcephaly), developmental delays and seizures.