News

Congratulations to Katherine A. Hajjar, MD, Vice Chair for Research and Brine Family Professor of Cell and Developmental Biology in the Department of Pediatrics at Weill Cornell Medicine, on being awarded a grant by the United States Department of Defense to develop treatment for proliferative vitreoretinopathy, a potentially blinding disease that occurs in almost one-half of military personnel who sustain a penetrating wound to the eye.

Proliferative vitreoretinopathy (PVR) occurs in some patients who have had complicated eye surgeries. When there is a tear in the retina, cells inside the eye, known as RPE cells, that normally remain behind the retina, begin to proliferate, move away from their normal position, and migrate to the inner surface of the retina. Over time, these migratory cells form a scar-like membrane that pulls the remaining retina away from the back of the eye, severely compromising vision. PVR is increasing in frequency among military personnel due to the increasing use of explosive devices in modern combat. Unfortunately, however, there is no treatment for this devastating disease.

Congratulations to David C. Lyden, MD, PhD, Stavros S. Niarchos Professor in Pediatric Cardiology at Weill Cornell Medicine, who, together with Drs. Linnie Golightly, Associate Professor of Clinical Medicine, Shahin Rafii, Professor of Medicine and Raphael Lis, Assistant Professor of Reproductive Medicine in Medicine, received an R61 award titled, "In vitro modeling of brain blood barrier dysfunction on a chip to elucidate the pathogenesis of cerebral malaria."

Congratulations to Emily Wasserman, MD on receiving a $25,000 award from the HHV-6 Foundation for her project entitled, Association of Multi-system inflammatory syndrome in children and chromosomally integrated HHV6.

For this project, Dr. Wasserman and her team at Weill Cornell Medicine will determine the prevalence of chromosomally integrated human herpes virus 6 (ici‐HHV6) in a cohort of patients with multisystem inflammatory syndrome in children (MIS‐C).  HHV‐6 reactivation has been associated with hyperinflammatory states and a recent case report identified ici‐HHV6 in a patient with MIS‐C. Dr. Wasserman believes an association between ici‐HHV6 and MIS‐C would shed light on the pathogenesis of MIS‐C and hyperinflammatory responses to SARS-CoV2. 

The Global Team Science Award project led by Dr. Virginia Pascual, Director of the Gale and Ira Drukier Institute for Children's Health and Ronay Menschel Professor of Pediatrics aims to study childhood-onset systemic lupus erythematosus (cSLE). Children often suffer from severe lupus symptoms as well as from side effects of current therapies; children with lupus often have a strong connection between their genetic makeup (DNA) and their disease; children also lack other illnesses that could complicate the understanding of research findings.

Congratulations to the 25 Physicians from the Department of Pediatrics who made this year's Super Doctors and Rising Stars list. The list recognizes outstanding doctors from more than 40 medical specialties who have attained a high degree of peer recognition or professional achievement.

The selection process for Super Doctors and Rising Stars is a rigorous multi-step process designed to identify healthcare providers who have attained a high degree of peer recognition and professional achievement.

Super Doctors

Dr. Zoltan Antal | Pediatrics Endocrinology
Dr. Sheila J. Carroll | Pediatrics Cardiology
Dr. Lilian L. Cohen | Pediatrics Genetic Medicine
Dr. Jennifer F. Cross | Pediatrics
Dr. Christopher Cunniff | Pediatrics Genetic Medicine
Dr. Bruce M. Greenwald | Pediatrics Critical Care Medicine
Dr. Neera Gupta | Pediatrics Gastroenterology
Dr. James Killinger | Pediatrics Critical Care Medicine
Dr. Barry Kosofsky | Pediatrics Neurology
Dr. Gerald Loughlin | Pediatrics Pulmonary Medicine
Dr. Marianne E. Nellis | Pediatrics Critical Care Medicine

In recognition of Women In Medicine Month, we are highlighting women in the Department of Pediatrics who have worked throughout their careers to foster an environment that uplifts and supports women in medicine. Distinguished by their leadership and expertise in pediatric care, the doctors offer career advice and share the obstacles women still face in healthcare and why having women in leadership is so important. 

Susan Bostwick, MDSusan Bostwick, MD

 Dr. Susan Bostwick, Professor of Clinical Pediatrics, is Executive Vice Chair for Administration and Faculty in the Department of Pediatrics and Chief of the Division of General Academic Pediatrics at Weill Cornell Medicine. In addition, she is the Associate Dean for Affiliations at Weill Cornell. Prior to the Department of Pediatrics she served as the Vice Chair for Education (2010-2021), Director of Pediatric Graduate Medical Education at NewYork-Presbyterian Hospital, Weill Cornell Campus (1999-2010, Associate Director 2010-2012), Medical Director of Inpatient General Pediatrics (1997-2003) and the Physician Liaison to Information Technology at NewYork-Presbyterian/Weill Cornell Medical Center (2007-2021)

What obstacles are women in medicine still facing when it comes to inclusion, equity and diversity?

One of the obstacles that women face is since we are still underrepresented at many of the decision making "tables", decisions are made without our opinions being voiced, and yet it remains difficult to get a seat at the table. With almost 30 years of medical schools having close to even split in gender, the upper echelons, e.g. chairs, professors, CEOs, etc., are still not as equally representative. Continuing to ensure that women's voices are heard and that women have the opportunities to lead and make decisions is a continuing part of the challenges.

Congratulations to Lisa Giulino Roth, M.D.Director of Pediatric Oncology and Associate Professor in the Departments of Pediatrics, Medicine, Pathology and Laboratory Medicine at Weill Cornell Medicine, on being awarded the 2021 Hyundai Hope Scholar Grant, funded by Hyundai Hope On Wheels, for her project, Targeting latent viral antigens in EBV+ Burkitt Lymphoma.

For this study, Dr. Roth is developing a novel approach to the treatment of lymphomas associated with Epstein Barr Virus (EBV).  Using epigenetic therapies, Dr. Roth and her laboratory team will determine if they can alter the proteins expressed by EBV and make the tumor more susceptible to killing by immune cells.  If successful, the work will lead to a completely new treatment approach for lymphomas associated with EBV.

Congratulations to Eric Mallack, M.D., Director of the Leukodystrophy Center and Assistant Professor of Pediatrics and Neurology at Weill Cornell Medicine, on being awarded a K23 award from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health entitled, “Leveraging myelin-sensitive imaging to predict early lesion pathogenesis in cerebral adrenoleukodystrophy.

Cerebral Adrenoleukodystrophy (CALD) is a neurologically devastating, inflammatory demyelinating disease of childhood that leads to a vegetative state or death in months to years. Treatments are most effective when initiated in the narrow window prior to the onset of neurological symptoms, however early identification of CALD is a significant challenge.  In this project, Dr. Mallack and his collaborators at Weill Cornell Medical College and Harvard Medical School will study the transition from normal brain development to cerebral demyelination using advanced imaging techniques in order to widen the treatment window, provide lead-time for possible preventative strategies, and thereby help maximize neurological outcomes.

Dr. Alexander Ja-Ho Chou is an assistant professor of pediatrics at Weill Cornell Medicine and an attending pediatrician at NewYork-Presbyterian/Weill Cornell Medical Center. He specializes in the care of children with pediatric sarcomas including osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, synovial sarcoma, desmoplastic small round cell tumor, alveolar soft part sarcoma, rhabdoid tumors, epithelioid sarcomas, infantile fibrosarcomas, and other rare sarcomas of childhood, and also cares for children with other common solid tumors such as neuroblastoma, Wilm's tumor, hepatoblastoma, germ cell tumors, and other rarer tumors of childhood.

What made you want to become a pediatrician AND an oncologist?

The mental health crisis among our pediatric patients has been exacerbated by the COVID-19 pandemic. Now more than ever, children, adolescents, and their families need access to mental health care and resources.

Since the start of the pandemic, pediatricians at Weill Cornell Medicine and NewYork-Presbyterian Hospital have witnessed increased rates of suicidality in their patients, in an addition to increased depression, eating problems, and anxiety. As a result, more youth are being admitted to the emergency room for inpatient mental health care.

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